V17M (p.Val17Met) variant of IRF4 (Interferon regulatory factor 4)
V17M (p.Val17Met) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
V17M (p.Val17Met) variant details
- p.Val17Met
- gnomAD 6-393201-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.42
- CADD 23.50
- PolyPhen-2 0.11
- SIFT 0.14
- MutPred 0.54
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available