S34R (p.Ser34Arg) variant of IRF4 (Interferon regulatory factor 4)
S34R (p.Ser34Arg) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
S34R (p.Ser34Arg) variant details
- p.Ser34Arg
- gnomAD 6-393254-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.626
- REVEL 0.82
- CADD 25.70
- PolyPhen-2 0.93
- SIFT 0.00
- MutPred 0.89
- Population evidence available
- Structural context available
- Literature evidence available