S34I (p.Ser34Ile) variant of IRF4 (Interferon regulatory factor 4)
S34I (p.Ser34Ile) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data, published literature, and structural context.
S34I (p.Ser34Ile) variant details
- p.Ser34Ile
- gnomAD 6-393253-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.86
- REVEL 0.89
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- MutPred 0.88
- Population evidence available
- Structural context available
- Literature evidence available