S18G (p.Ser18Gly) variant of IRF4 (Interferon regulatory factor 4)
S18G (p.Ser18Gly) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
S18G (p.Ser18Gly) variant details
- p.Ser18Gly
- TOPMed rs1343907006
- gnomAD rs1343907006
- Missense
- Variant Prioritization Score for Impact Estimate 0.645
- REVEL 0.72
- CADD 26.40
- PolyPhen-2 0.87
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available