S15I (p.Ser15Ile) variant of IRF4 (Interferon regulatory factor 4)
S15I (p.Ser15Ile) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
S15I (p.Ser15Ile) variant details
- p.Ser15Ile
- gnomAD 6-393196-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.35
- CADD 24.30
- PolyPhen-2 0.06
- SIFT 0.02
- MutPred 0.39
- Population evidence available
- Structural context available
- Literature evidence available