R8G (p.Arg8Gly) variant of IRF4 (Interferon regulatory factor 4)
R8G (p.Arg8Gly) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
R8G (p.Arg8Gly) variant details
- p.Arg8Gly
- gnomAD rs1251757585
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.33
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.10
- MutPred 0.36
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available