R25S (p.Arg25Ser) variant of IRF4 (Interferon regulatory factor 4)
R25S (p.Arg25Ser) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
R25S (p.Arg25Ser) variant details
- p.Arg25Ser
- gnomAD 6-393225-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.773
- REVEL 0.93
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.88
- Population evidence available
- Structural context available
- Literature evidence available