P38L (p.Pro38Leu) variant of IRF4 (Interferon regulatory factor 4)
P38L (p.Pro38Leu) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
P38L (p.Pro38Leu) variant details
- p.Pro38Leu
- ExAC rs755738102
- Missense
- Variant Prioritization Score for Impact Estimate 0.856
- REVEL 0.89
- CADD 29.70
- PolyPhen-2 0.96
- SIFT 0.00
- MutPred 0.81
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available