P38A (p.Pro38Ala) variant of IRF4 (Interferon regulatory factor 4)
P38A (p.Pro38Ala) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
P38A (p.Pro38Ala) variant details
- p.Pro38Ala
- gnomAD 6-393264-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.76
- CADD 22.60
- PolyPhen-2 0.12
- SIFT 0.49
- MutPred 0.80
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available