N2K (p.Asn2Lys) variant of IRF4 (Interferon regulatory factor 4)
N2K (p.Asn2Lys) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
N2K (p.Asn2Lys) variant details
- p.Asn2Lys
- gnomAD 6-393158-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.493
- REVEL 0.47
- CADD 23.90
- PolyPhen-2 0.15
- SIFT 0.00
- MutPred 0.29
- Population evidence available
- Structural context available
- Literature evidence available