N21K (p.Asn21Lys) variant of IRF4 (Interferon regulatory factor 4)
N21K (p.Asn21Lys) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
N21K (p.Asn21Lys) variant details
- p.Asn21Lys
- gnomAD 6-393215-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.48
- CADD 23.30
- PolyPhen-2 0.73
- SIFT 0.09
- MutPred 0.51
- Population evidence available
- Structural context available
- Literature evidence available