M14V (p.Met14Val) variant of IRF4 (Interferon regulatory factor 4)
M14V (p.Met14Val) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
M14V (p.Met14Val) variant details
- p.Met14Val
- gnomAD 6-393192-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.53
- CADD 24.10
- PolyPhen-2 0.01
- SIFT 0.03
- MutPred 0.44
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available