L40W (p.Leu40Trp) variant of IRF4 (Interferon regulatory factor 4)
L40W (p.Leu40Trp) in IRF4 (Interferon regulatory factor 4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
L40W (p.Leu40Trp) variant details
- p.Leu40Trp
- gnomAD 6-393262-AC-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.627
- CADD 27.10
- Population evidence available
- Structural context available
- Literature evidence available