L3M (p.Leu3Met) variant of IRF4 (Interferon regulatory factor 4)
L3M (p.Leu3Met) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and published literature.
L3M (p.Leu3Met) variant details
- p.Leu3Met
- gnomAD 6-393159-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.36
- CADD 23.10
- PolyPhen-2 0.64
- SIFT 0.00
- MutPred 0.19
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Literature evidence available