L28P (p.Leu28Pro) variant of IRF4 (Interferon regulatory factor 4)
L28P (p.Leu28Pro) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
L28P (p.Leu28Pro) variant details
- p.Leu28Pro
- gnomAD 6-393235-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.852
- REVEL 0.98
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.92
- Population evidence available
- Structural context available
- Literature evidence available