L28M (p.Leu28Met) variant of IRF4 (Interferon regulatory factor 4)
L28M (p.Leu28Met) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
L28M (p.Leu28Met) variant details
- p.Leu28Met
- gnomAD 6-393234-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.687
- REVEL 0.83
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.90
- Population evidence available
- Structural context available
- Literature evidence available