L24I (p.Leu24Ile) variant of IRF4 (Interferon regulatory factor 4)
L24I (p.Leu24Ile) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
L24I (p.Leu24Ile) variant details
- p.Leu24Ile
- gnomAD 6-393222-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.775
- REVEL 0.76
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.81
- Population evidence available
- Structural context available
- Literature evidence available