K47N (p.Lys47Asn) variant of IRF4 (Interferon regulatory factor 4)
K47N (p.Lys47Asn) in IRF4 (Interferon regulatory factor 4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
K47N (p.Lys47Asn) variant details
- p.Lys47Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.73
- REVEL 0.87
- CADD 29.80
- PolyPhen-2 0.98
- SIFT 0.00
- MutPred 0.54
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available