K47E (p.Lys47Glu) variant of IRF4 (Interferon regulatory factor 4)
K47E (p.Lys47Glu) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
K47E (p.Lys47Glu) variant details
- p.Lys47Glu
- gnomAD 6-393291-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.765
- REVEL 0.90
- CADD 32.00
- PolyPhen-2 0.93
- SIFT 0.00
- MutPred 0.53
- Population evidence available
- Structural context available
- Literature evidence available