K36Q (p.Lys36Gln) variant of IRF4 (Interferon regulatory factor 4)
K36Q (p.Lys36Gln) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
K36Q (p.Lys36Gln) variant details
- p.Lys36Gln
- gnomAD 6-393258-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- REVEL 0.46
- CADD 25.40
- PolyPhen-2 0.03
- SIFT 0.02
- MutPred 0.32
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available