K36E (p.Lys36Glu) variant of IRF4 (Interferon regulatory factor 4)
K36E (p.Lys36Glu) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
K36E (p.Lys36Glu) variant details
- p.Lys36Glu
- gnomAD 6-393258-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.62
- CADD 25.90
- PolyPhen-2 0.04
- SIFT 0.04
- MutPred 0.34
- Population evidence available
- Structural context available
- Literature evidence available