K23E (p.Lys23Glu) variant of IRF4 (Interferon regulatory factor 4)
K23E (p.Lys23Glu) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, published literature, and structural context.
K23E (p.Lys23Glu) variant details
- p.Lys23Glu
- gnomAD 6-393219-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.836
- REVEL 0.95
- CADD 32.00
- PolyPhen-2 0.97
- SIFT 0.00
- MutPred 0.81
- Population evidence available
- Structural context available
- Literature evidence available