I49V (p.Ile49Val) variant of IRF4 (Interferon regulatory factor 4)
I49V (p.Ile49Val) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
I49V (p.Ile49Val) variant details
- p.Ile49Val
- gnomAD 6-393297-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.32
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 0.19
- MutPred 0.59
- Population evidence available
- Structural context available
- Literature evidence available