I49F (p.Ile49Phe) variant of IRF4 (Interferon regulatory factor 4)
I49F (p.Ile49Phe) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
I49F (p.Ile49Phe) variant details
- p.Ile49Phe
- gnomAD 6-393297-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.67
- CADD 23.80
- PolyPhen-2 0.42
- SIFT 0.04
- MutPred 0.74
- Population evidence available
- Structural context available
- Literature evidence available