I32M (p.Ile32Met) variant of IRF4 (Interferon regulatory factor 4)
I32M (p.Ile32Met) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
I32M (p.Ile32Met) variant details
- p.Ile32Met
- gnomAD 6-393248-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- REVEL 0.78
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.86
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available