G7S (p.Gly7Ser) variant of IRF4 (Interferon regulatory factor 4)
G7S (p.Gly7Ser) in IRF4 (Interferon regulatory factor 4) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G7S (p.Gly7Ser) variant details
- p.Gly7Ser
- NCI-TCGA Cosmic COSV1011
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.26
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.80
- MutPred 0.20
- ClinVar: Uncertain significance (not provided)
- UniProt: Uncertain significance
- Population evidence available
- Structural context available