G6C (p.Gly6Cys) variant of IRF4 (Interferon regulatory factor 4)
G6C (p.Gly6Cys) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and published literature.
G6C (p.Gly6Cys) variant details
- p.Gly6Cys
- gnomAD 6-393168-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.38
- CADD 19.10
- PolyPhen-2 0.56
- SIFT 0.03
- MutPred 0.40
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Literature evidence available