G5A (p.Gly5Ala) variant of IRF4 (Interferon regulatory factor 4)
G5A (p.Gly5Ala) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
G5A (p.Gly5Ala) variant details
- p.Gly5Ala
- gnomAD 6-393166-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.25
- CADD 20.50
- PolyPhen-2 0.00
- SIFT 0.27
- MutPred 0.16
- Most common in the Non-Finnish European population (allele frequency 1.8e-05)
- Structural context available
- Literature evidence available