G39R (p.Gly39Arg) variant of IRF4 (Interferon regulatory factor 4)
G39R (p.Gly39Arg) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.91 / 1. The record also includes population frequency data, published literature, and structural context.
G39R (p.Gly39Arg) variant details
- p.Gly39Arg
- gnomAD 6-393267-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.912
- REVEL 0.98
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.98
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available