G35V (p.Gly35Val) variant of IRF4 (Interferon regulatory factor 4)
G35V (p.Gly35Val) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
G35V (p.Gly35Val) variant details
- p.Gly35Val
- gnomAD 6-393256-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.866
- REVEL 0.92
- CADD 31.00
- PolyPhen-2 0.90
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available