G22R (p.Gly22Arg) variant of IRF4 (Interferon regulatory factor 4)
G22R (p.Gly22Arg) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- gnomAD 6-393216-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.673
- REVEL 0.68
- CADD 26.60
- PolyPhen-2 0.58
- SIFT 0.06
- MutPred 0.44
- Population evidence available
- Structural context available
- Literature evidence available