G20S (p.Gly20Ser) variant of IRF4 (Interferon regulatory factor 4)
G20S (p.Gly20Ser) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G20S (p.Gly20Ser) variant details
- p.Gly20Ser
- Ensembl rs1761164334
- Missense
- Variant Prioritization Score for Impact Estimate 0.736
- REVEL 0.69
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.02
- MutPred 0.48
- Most common in the East Asian population (allele frequency 2.7e-05)
- Structural context available