G20R (p.Gly20Arg) variant of IRF4 (Interferon regulatory factor 4)
G20R (p.Gly20Arg) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
G20R (p.Gly20Arg) variant details
- p.Gly20Arg
- gnomAD 6-393210-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.78
- REVEL 0.77
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.04
- MutPred 0.51
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available