G20D (p.Gly20Asp) variant of IRF4 (Interferon regulatory factor 4)
G20D (p.Gly20Asp) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
G20D (p.Gly20Asp) variant details
- p.Gly20Asp
- Ensembl rs1761164408
- Missense
- Variant Prioritization Score for Impact Estimate 0.812
- REVEL 0.82
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- MutPred 0.56
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available