G10A (p.Gly10Ala) variant of IRF4 (Interferon regulatory factor 4)
G10A (p.Gly10Ala) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and published literature.
G10A (p.Gly10Ala) variant details
- p.Gly10Ala
- gnomAD 6-393181-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.34
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.27
- MutPred 0.15
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Literature evidence available