D33G (p.Asp33Gly) variant of IRF4 (Interferon regulatory factor 4)
D33G (p.Asp33Gly) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, published literature, and structural context.
D33G (p.Asp33Gly) variant details
- p.Asp33Gly
- gnomAD 6-393250-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.837
- REVEL 0.95
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- MutPred 0.66
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available