A16T (p.Ala16Thr) variant of IRF4 (Interferon regulatory factor 4)
A16T (p.Ala16Thr) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A16T (p.Ala16Thr) variant details
- p.Ala16Thr
- Ensembl rs2127436076
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.21
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.17
- MutPred 0.22
- Most common in the East Asian population (allele frequency 2.7e-05)
- Structural context available