A16S (p.Ala16Ser) variant of IRF4 (Interferon regulatory factor 4)
A16S (p.Ala16Ser) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
A16S (p.Ala16Ser) variant details
- p.Ala16Ser
- gnomAD 6-393198-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.21
- CADD 17.70
- PolyPhen-2 0.00
- SIFT 0.99
- MutPred 0.31
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available