Y10C (p.Tyr10Cys) variant of IRAK4 (Q9NWZ3)
Y10C (p.Tyr10Cys) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
Y10C (p.Tyr10Cys) variant details
- p.Tyr10Cys
- gnomAD 12-43768140-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.648
- CADD 26.80
- PolyPhen-2 0.89
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available