W32R (p.Trp32Arg) variant of IRAK4 (Q9NWZ3)
W32R (p.Trp32Arg) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
W32R (p.Trp32Arg) variant details
- p.Trp32Arg
- gnomAD 12-43768205-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- CADD 28.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available