W32* (p.Trp32Ter) variant of IRAK4 (Q9NWZ3)
W32* (p.Trp32Ter) in IRAK4 (Q9NWZ3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
W32* (p.Trp32Ter) variant details
- p.Trp32Ter
- 1000Genomes rs1199041696
- gnomAD rs1199041696
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.847
- CADD 36.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available