T76I (p.Thr76Ile) variant of IRAK4 (Q9NWZ3)
T76I (p.Thr76Ile) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
T76I (p.Thr76Ile) variant details
- p.Thr76Ile
- ESP rs200175187
- ExAC rs200175187
- TOPMed rs200175187
- gnomAD rs200175187
- Missense
- Variant Prioritization Score for Impact Estimate 0.781
- CADD 25.40
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available