T62S (p.Thr62Ser) variant of IRAK4 (Q9NWZ3)
T62S (p.Thr62Ser) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
T62S (p.Thr62Ser) variant details
- p.Thr62Ser
- ExAC rs751881820
- gnomAD rs751881820
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- CADD 14.40
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the African/African-American population (allele frequency 3e-05)