S8* (p.Ser8Ter) variant of IRAK4 (Q9NWZ3)
S8* (p.Ser8Ter) in IRAK4 (Q9NWZ3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
S8* (p.Ser8Ter) variant details
- p.Ser8Ter
- gnomAD 12-43768134-C-G
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.845
- CADD 35.00
- Population evidence available
- Structural context available
- Literature evidence available