S68S (p.Ser68Ser) variant of IRAK4 (Q9NWZ3)
S68S (p.Ser68Ser) in IRAK4 (Q9NWZ3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
S68S (p.Ser68Ser) variant details
- p.Ser68Ser
- gnomAD 12-43771262-T-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.355
- AlphaMissense 0.19
- MetaLR 0.13
- MetaSVM -0.98
- CADD 11.60
- SIFT 0.26
- MutPred 0.47
- Population evidence available
- Structural context available
- Literature evidence available