Q61K (p.Gln61Lys) variant of IRAK4 (Q9NWZ3)
Q61K (p.Gln61Lys) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data.
Q61K (p.Gln61Lys) variant details
- p.Gln61Lys
- TOPMed rs1266375962
- gnomAD rs1266375962
- Missense
- Variant Prioritization Score for Impact Estimate 0.567
- AlphaMissense 0.10
- MetaLR 0.20
- MetaSVM -0.87
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)