P42T (p.Pro42Thr) variant of IRAK4 (Q9NWZ3)
P42T (p.Pro42Thr) in IRAK4 (Q9NWZ3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
P42T (p.Pro42Thr) variant details
- p.Pro42Thr
- rs1940376224
- gnomAD 12-43768228-T-TA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.371
- CADD 26.00
- Population evidence available
- Structural context available
- Literature evidence available