P42S (p.Pro42Ser) variant of IRAK4 (Q9NWZ3)
P42S (p.Pro42Ser) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
P42S (p.Pro42Ser) variant details
- p.Pro42Ser
- gnomAD 12-43768235-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.766
- CADD 24.30
- PolyPhen-2 0.73
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available