N2S (p.Asn2Ser) variant of IRAK4 (Q9NWZ3)
N2S (p.Asn2Ser) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
N2S (p.Asn2Ser) variant details
- p.Asn2Ser
- 1000Genomes rs561048547
- gnomAD rs561048547
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- CADD 4.57
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available