N15Y (p.Asn15Tyr) variant of IRAK4 (Q9NWZ3)
N15Y (p.Asn15Tyr) in IRAK4 (Q9NWZ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
N15Y (p.Asn15Tyr) variant details
- p.Asn15Tyr
- gnomAD 12-43768154-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- CADD 22.50
- PolyPhen-2 0.23
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available